| Rank | Player | Team | Assists |
| 1 | M. Havlat | SJS | 48 |
| 2 | P. Kane | CHI | 45 |
| 3 | B. Campbell | FLA | 45 |
| 4 | D. Keith | CHI | 36 |
| 5 | J. Toews | CHI | 35 |
| 6 | A. Ladd | WPG | 34 |
| 7 | C. Barker | VAN | 34 |
| 8 | K. Versteeg | FLA | 31 |
| 9 | D. Bolland | CHI | 28 |
| 10 | P. Sharp | CHI | 18 |
| 11 | B. Seabrook | CHI | 18 |
| 12 | D. Byfuglien | WPG | 16 |
| 13 | T. Brouwer | WSH | 16 |
| 14 | M. Walker | PHI | 13 |
| 15 | C. Fraser | LAK | 11 |
| 16 | J. Wisniewski | CBJ | 11 |
| 17 | A. Johnson | BOS | 5 |
| 18 | B. Eager | EDM | 4 |
| 19 | C. Adams | PIT | 4 |
| 20 | A. Burish | SJS | 3 |